POST OPERATIVE COMPLICATIONS IN PATIENTS OF PARTIAL NEPHRECTOMY

F ZEHRA; HH QURESHI; SZ ABBAS; N MAHAR; A LALAWANI; AS HASSAN; AUH RIZVI

doi:10.54112/pjicm.v5i02.207

Authors

F ZEHRA The Department of Urology, Sindh Institute of Urology and Transplantation (SIUT), Sardar Yaqoob Ali Khan Road, Karachi, Pakistan
HH QURESHI The Department of Urology, Sindh Institute of Urology and Transplantation (SIUT), Sardar Yaqoob Ali Khan Road, Karachi, Pakistan
SZ ABBAS The Department of Urology, Sindh Institute of Urology and Transplantation (SIUT), Sardar Yaqoob Ali Khan Road, Karachi, Pakistan
N MAHAR The Department of Urology, Sindh Institute of Urology and Transplantation (SIUT), Sardar Yaqoob Ali Khan Road, Karachi, Pakistan
A LALAWANI The Department of Urology, Sindh Institute of Urology and Transplantation (SIUT), Sardar Yaqoob Ali Khan Road, Karachi, Pakistan
AS HASSAN The Department of Urology, Sindh Institute of Urology and Transplantation (SIUT), Sardar Yaqoob Ali Khan Road, Karachi, Pakistan
AUH RIZVI The Department of Urology, Sindh Institute of Urology and Transplantation (SIUT), Sardar Yaqoob Ali Khan Road, Karachi, Pakistan

DOI:

https://doi.org/10.54112/pjicm.v5i02.207

Keywords:

Partial Nephrectomy, Postoperative Complications, Renal Cell Carcinoma, Tumour Location, Clavien-Dindo Classification, Nephrometry Score

Abstract

Background: Partial nephrectomy is a well-established surgical approach for localized renal cell carcinoma, aiming to preserve renal function while achieving oncologic control. Postoperative complications remain a concern and may vary according to tumor location and anatomical complexity, as assessed by nephrometry scoring systems. Objective: To determine the frequency and pattern of postoperative complications in patients with renal cell carcinoma undergoing open partial nephrectomy in relation to tumor location. Study Design: Descriptive observational study. Setting: The Department of Urology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan. Duration of Study: From 11th May 2023 to 10th November 2023. Methods: Fifty adult patients who underwent open partial nephrectomy for renal cell carcinoma were included. Preoperative imaging was used to determine tumor location and assign the R.E.N.A.L. nephrometry score for complexity grading. Patients were followed postoperatively for one month. Complications were documented using predefined clinical and radiological criteria and classified according to the Clavien–Dindo classification system. Data were analyzed using descriptive statistics with SPSS version 22. Results: The mean age of patients was 52.14 ± 13.58 years, with a male predominance (74.0%). Most tumors were of moderate complexity (56.0%). The upper pole was the most common tumor location (38.0%). According to the Clavien–Dindo classification, 60.0% of patients experienced no postoperative complications, 30.0% had minor complications (Grade I–II), and 10.0% developed major complications (Grade IIIa–IIIb). Postoperative bleeding was the most frequent complication (22.0%), followed by fever (14.0%) and atelectasis (8.0%). Urinary leakage occurred in 10.0% of cases. Conclusion: Open partial nephrectomy demonstrated an acceptable postoperative safety profile. Bleeding, fever, atelectasis, and urinary leakage were the most commonly observed complications, with upper pole and centrally located tumors being the most frequent anatomical sites involved.

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