ASSESSMENT OF THE OUTCOME OF SEPSIS PATIENTS ADMITTED TO THE INTENSIVE CARE UNIT

R PERVAIZ; B ARIF; MS HASHMI; H AHMED; . ADEEL; A ASGHAR; S ZARTASH

doi:10.54112/pjicm.v3i01.21

Authors

R PERVAIZ Department of Critical Care Medicine, Bahria International Hospital, Lahore, Pakistan
B ARIF Department of Critical Care Medicine, Bahria International Hospital, Lahore, Pakistan
MS HASHMI Department of Critical Care Medicine, Bahria International Hospital, Lahore, Pakistan
H AHMED Department of Critical Care Medicine, Bahria International Hospital, Lahore, Pakistan
. ADEEL Department of Critical Care Nursing, Bahria International Hospital, Lahore, Pakistan
A ASGHAR Department of Critical Care Nursing, Bahria International Hospital, Lahore, Pakistan
S ZARTASH Department of Critical Care Medicine, Services Institute of Medical Sciences, Lahore, Pakistan

DOI:

https://doi.org/10.54112/pjicm.v3i01.21

Keywords:

Sepsis, Septic Shock, Intensive Care Unit, Mortality, Risk Factors, Blood Culture, Outcome Assessment, Respiratory Complications, Renal Complications, Neurological Complications

Abstract

Background: Sepsis remains a significant challenge in critical care medicine, with high morbidity and mortality rates, particularly among patients admitted to the intensive care unit (ICU). Understanding sepsis outcomes in the ICU is crucial for guiding clinical management decisions and improving patient care practices. Objective: This study aimed to assess the consequences of severe sepsis and septic shock in patients admitted to the ICU at Bahria Town International Hospital Lahore, focusing on mortality rates, risk factors for death, and site of infection. Study Design: A prospective clinical study adhering to STROBE guidelines was conducted at the ICU of Bahria Town International Hospital Lahore from March 2023 to December 2023. Setting: The study was conducted at the Intensive Care Unit (ICU) of Bahria Town International Hospital Lahore. Duration of Study: The study was conducted from March 2023 to December 2023. Material and Methods: Patients aged 18 years and older admitted to the ICU with severe sepsis or septic shock were included. Exclusion criteria included ICU length of stay shorter than 24 hours and patients under 18 years old. Data on demographics, infection source, comorbidities, laboratory results, hospital stay, and outcomes were prospectively collected using a predefined form. Data analysis was performed using SPSS 21 software, including descriptive statistics and binary logistic regression, to identify variables affecting patient survival. Results: Sixty individuals were enrolled, with a mean age of 55.55 ± 20.32 years. The majority were male (58.3%). The mean length of hospital stay was 6.43 ± 3.54 days. Among the study population, 43.3% had severe sepsis, and 56.6% had septic shock. The mortality rate was 41.6%. Positive blood culture was associated with a higher mortality rate, and patients with septic shock had a significantly increased risk of death. Complications with the respiratory, renal, and central neurological systems also increased the likelihood of death. Conclusion: This study highlights the significant mortality associated with severe sepsis and septic shock in ICU patients. Positive blood culture and septic shock were identified as important predictors of mortality. Early recognition and management of these factors are essential for improving patient outcomes in sepsis.

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